Episode 171: CRISPR for Sickle Cell Disease: The Real Story

Episode 171: CRISPR for Sickle Cell Disease: The Real Story

On this special episode of Healthcare Unfiltered, I am joined by my esteemed guest James LaBelle, MD, PhD, Associate Director of Pediatrics and Director of the Stem Cell and Cellular Therapy Program at the University of Chicago. James is the senior author on the NEJM paper that showed how CRISPR technology can cure sickle cell disease. Link to the paper below.

On the show, Dr. LaBelle elucidates the complexities of sickle cell disease, unraveling the devastating impact it has on individuals. The episode delves into various treatments and approaches to combat this formidable disease, including bone marrow transplant and the groundbreaking use of CRISPR-Cas9 technology. LaBelle shares insights into the recent research breakthroughs, citing the remarkable research report published in the New England Journal of Medicine, showcasing the successful application of CRISPR-Cas9 for sickle cell disease. This episode serves as a gateway into the promising future of genetic therapies, offering hope and understanding for those affected by this challenging condition.

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