In this special episode of Healthcare Unfiltered, I delve into the realm of AI and its transformative impact on drug development with Adam Petrich, MD, Chief Medical Officer of QuantHealth. Adam unveils the AI solutions crafted by QuantHealth, aimed at simulating and predicting clinical trial outcomes to enhance the success rates of trials. Drawing from his expertise, he sheds light on the integration of AI in the clinical trial creation process, offering insights into predicting investigational treatment efficacy against standard of care treatments. Dr. Petrich also explores the delicate balance between sensitivity and specificity, and delves into the meticulous validation processes employed to ensure model accuracy.
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Dr. Simrit Parmar, founder of Cellenkos, joins the show to discuss her journey from the lab to the biotech startup world, detailing the inspiration behind launching her company, the challenges of securing funding, and the resilience required to overcome rejections. She shares insights into Cellenkos’ lead product, its progress toward market approval, and the rigorous
Carol Rausch—a healthcare professional, cancer researcher, and former patient with lymphoma—shares how her journey from researcher to patient transformed her understanding of medical language. She discusses the impact of word choice on patients, why certain battle and war metaphors can be harmful, and how language used in clinical settings differs from what resonates with those
Drs. David Braun and Toni Choueiri join to discuss a groundbreaking Nature study on a personalized neoantigen vaccine for adjuvant renal cell carcinoma. They explore the inspiration behind the trial, how the vaccine was developed and administered, and its safety profile. The conversation also covers patient outcomes after 3-4 years, including immune responses and disease
